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Re: Autoimmunity and depression » chumbawumba

Posted by mtom - on August 27, 2019, at 9:45:45

In reply to Re: Autoimmunity and depression, posted by chumbawumba on August 26, 2019, at 23:33:57

> I have Hashimoto's thyroiditis and is clearly linked to my depression. My thyroid is essentially dead and I have to take 200 mcg T4 and 40 mcg of T3 a day as replacement.

Yes they checked my thyroid when I developed depression, especially as I have another autoimmune condition and people with one autoimmune condition have higher risk for developing others. Have the replacement hormones had any effect on the depression?

People with Celiac Disease (also autoimmune) have a higher risk of developing Hashimoto's. Celiac by itself can cause depression. Have you been tested for it? Most people with Celiac have other symptoms including gastrointestinal, but it's recently been found that "silent Celiac" is more common than previously thought where some people don't have the typical overt symptoms.

I'm speculating that even if the hormones are replaced, the autoimmune process may still be active, i.e. inflammation? There are other threads discussing the inflammatory and autoimmune theories of depression you might look at.

Some of the anti-inflammatory supplements that have been discussed include omega-3's e.g. fish oil, especially EPA. I've seen other posters say it hasn't helped, but there are a number of research studies which did seem to find these were helpful at higher doses. While some studies did not - but I think studies often may not be long enough, I think it could take some time for the EPA to kick in, if it's going to.


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