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Re: Study said amitriptyline most effective? » mtom

Posted by linkadge on March 31, 2019, at 12:24:14

In reply to Study said amitriptyline most effective?, posted by mtom on March 29, 2019, at 11:48:52

Doctors are perhaps concerned with liability (i.e. TCAs are more lethal in overdose) and / or compliance than they are about effectiveness.

I would agree that amitriptyline or imipramine are probably the most effective (perhaps alongside the TCAs), but the effectiveness is offset by a higher dropout rate. In terms of improving the depression itself, amtitriptyline is effective.

Linkadge



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