Posted by linkadge on March 31, 2019, at 12:24:14
In reply to Study said amitriptyline most effective?, posted by mtom on March 29, 2019, at 11:48:52
Doctors are perhaps concerned with liability (i.e. TCAs are more lethal in overdose) and / or compliance than they are about effectiveness.
I would agree that amitriptyline or imipramine are probably the most effective (perhaps alongside the TCAs), but the effectiveness is offset by a higher dropout rate. In terms of improving the depression itself, amtitriptyline is effective.
Linkadge
poster:linkadge
thread:1103744
URL: http://www.dr-bob.org/babble/20190206/msgs/1103788.html