Posted by farshad on March 24, 2018, at 14:09:38
In reply to Re: How can I block Cortisol? » farshad, posted by ed_uk2010 on March 24, 2018, at 13:59:35
> >on wiki it says miconazole is an antagonist on Glucocorticoid receptor , wouldnt that affect the Cortisol releasing hormones also if u block that?
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> Hi Farshad,
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> Well... the glucocorticoid receptors are a different type of receptor to CRH receptors. They have a different role.
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> As far as I know, ketoconazole does not usually alter CRH levels much (from what I read on Pubmed). It may increase ACTH, however.
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> Miconazole is a drug used in creams, so I wouldn't look at that drug specifically.
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> Have you been to your doctor to discuss tests yet?
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>so it wouldnt work? what about Metyrapone? that inhibits 11b hydroxylase. wouldnt that lead to less CRH release? btw what happens if u have high 11-Deoxycortisol lvls? Since inhibiting 11b hydroxylase will increase 11-Deoxycortisol, im wondering what the conseuqneses of that is .. increased aldosterone??
no havent been to the doc yet. becus i dont know what to test for.
I asked you but you didnt answer. am I supposed to test for Cortisol and ACTH ? is it possible to test for CRF1?
poster:farshad
thread:1097352
URL: http://www.dr-bob.org/babble/20180212/msgs/1097649.html