Posted by farshad on March 24, 2018, at 11:22:14
In reply to Re: How can I block Cortisol?, posted by ed_uk2010 on March 24, 2018, at 0:17:59
> >guys just 1/2 last questions.. Are the CRH (Corticotropin-releasing hormone) receptor 1 and 2 part of the Glucocorticoids? and Miconazole will block that?
>
> Hi,
>
> CRH receptors aren't glucocorticoids, no.
>
> The natural glucocorticoid in the body is cortisol. Synthetic glucocorticoids used in medicine include prednisone, prednisolone and dexamethasone. Glucocorticoids act on glucocorticoid receptors and have numerous effects... for example, reduction of inflammation and elevation of blood glucose.
>
> >Miconazole will block that?
>
> Miconazole does not block CRH receptors.
>
> The related drug ketoconazole is used to treat Cushing's syndrome because it reduces the synthesis of cortisol, and may (possibly) be an antagonist of the glucocorticoid receptors. Miconazole itself is generally only used as a cream to treat fungal infections.but on wiki it says miconazole is an antagonist on Glucocorticoid receptor , wouldnt that affect the Cortisol releasing hormones also if u block that?
poster:farshad
thread:1097352
URL: http://www.dr-bob.org/babble/20180212/msgs/1097645.html