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NE strengths of Reboxetine vs Atomoxetine

Posted by JohnBoy2000 on October 12, 2017, at 4:20:51

The IC 50 values I found for

Atomoxetine = 0.36 nM

Reboxetine = 8.2 nM

Perhaps there are more accurate IC50 values out there though.

Atomoxetine is dosed up to 100 mg
Reboxetine to 10 mg max.

Reboxetine supposedly failed clinical trials as an AD, but was approved anyways.

Atomoxetine supposedly failed clinical trails as an AD, but was approved for ADHD.


For myself - I've only ever responded to NE enhancing drugs so, I'm just looking for the most powerful one in that capacity.

According to them IC50 values - that would be atomoxetine, right?

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URL: http://www.dr-bob.org/babble/20161215/msgs/1095398.html