Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: NE strengths of Reboxetine vs Atomoxetine

Posted by linkadge on October 12, 2017, at 15:03:30

In reply to NE strengths of Reboxetine vs Atomoxetine, posted by JohnBoy2000 on October 12, 2017, at 4:20:51

Possibly.

According to Wikipedia,

Atomoxetine NET ki 5
Reboxetine NET ki 13.4

The problem with ki, is it connects the binding of the molecule to the concentration of the drug. The issue with this, is that taking 10mg of either drug, wouldn't necessarily result in the same drug concentration in the brain. The concentration is affected by rate of absorption, elimination half-life, brain penetrability etc.

My guess is that higher doses of atomoxetine are needed because it isn't as well absorbed as reboxetine, but I have no idea.

Linkadge



Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:linkadge thread:1095398
URL: http://www.dr-bob.org/babble/20161215/msgs/1095405.html