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Re: Morning Terror. Please, please read this. » porkpiehat

Posted by SLS on August 5, 2016, at 10:40:43

In reply to Re: Morning Terror. Please, please read this. » SLS, posted by porkpiehat on August 5, 2016, at 9:55:42

> > Prazosin is a NE alpha blocker, not a beta blocker. It is a crappy antihypertensive that doctors later found is a good PTSD drug for nightmares, depression, and anxiety. There can be some weight gain and reduction in sex-drive. Otherwise, it is a very clean drug.
>
> Scott: did it feel different at lower doses? I tried it during the day yesterday and it left me feeling flat-footed and more shy around people. Just 1 mg though. Not sure if it's worth moving up. No hypotensive issues probably bc I take 2mg at night.
>
> Wow it is so nice to be free of nightmares, night terrors, and hour-long panic attacks!

The psychotropic side-effects you are experiencing might pass quickly with continued treatment. I would recommend that you to push the dosage to 12 mg/day (4 mg t.i.d.) using a more robust titration schedule. I take 30 mg/day. If I reduce the dosage to 25 mg/day I lose much of the improvement it gives me. The maximum allowable dosage according to the manufacturer is 40 mg/day. I found that I experienced improvements in mood upon dosage increases that would quickly disappear until the next dosage increase. Finally, the improvement became stable at 30 mg/day.

Prazosin has a very short half-life (2-3 hours). If you run into problems, you can always discontinue it. It will leave the body quickly.

I can't imaging that I am the only one who experiences a robust improvement when using prazosin. My case is one of Bipolar I depression with drug-induced manias. It is probably the result of biological vulnerabilities being subjected to chronic psychosocial stress in the form of physical abuse, emotional abuse, and neglect experienced in childhood (developmental PTSD/complex trauma). My depression looks much like atypical depression. Anergia, anhedonia, and cognitive and memory impairments predominate. Depression began as mild at age 10, moderate at age 15, and severe at age 17.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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