Posted by TriedEveryMedication on June 4, 2016, at 11:24:55
In reply to Re: Ketamine lifts depression via a metabolite:, posted by SLS on May 4, 2016, at 14:45:31
> BDNF production is increased by AMPA receptor activation.
>
> That HNK is active in models of depression is not new. What is new is the discovery that glutamate AMPA receptors were involved in its pharmacology. Of course, this is not the end of the story. Increases in BDNF production (brain-derived neurotrophic factor) is a common denominator in the results of many antidepressant substances when they are effective.
>
>
> - Scott
ampakines like Aniracetam activate AMPA... Would you expect them to be helpful for depression?
poster:TriedEveryMedication
thread:1088670
URL: http://www.dr-bob.org/babble/20160501/msgs/1089435.html