Re: Ketamine lifts depression via a metabolite:

Posted by SLS on May 4, 2016, at 14:45:31

In reply to Ketamine lifts depression via a metabolite:, posted by PeterMartin on May 4, 2016, at 12:58:48

BDNF production is increased by AMPA receptor activation.
That HNK is active in models of depression is not new. What is new is the discovery that glutamate AMPA receptors were involved in its pharmacology. Of course, this is not the end of the story. Increases in BDNF production (brain-derived neurotrophic factor) is a common denominator in the results of many antidepressant substances when they are effective.

- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw

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Ketamine lifts depression via a metabolite: PeterMartin 5/4/16
Re: Ketamine lifts depression via a metabolite: SLS 5/4/16
Re: Ketamine lifts depression via a metabolite: » SLS TriedEveryMedication 6/4/16
Re: Ketamine lifts depression via a metabolite: » TriedEveryMedication SLS 6/4/16
Re: Ketamine lifts depression via a metabolite: Deahoidar 6/10/16

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