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Re: Venlafaxin mode of action? » Lamdage22
Posted by TriedEveryMedication on May 9, 2016, at 19:02:21
In reply to Venlafaxin mode of action?, posted by Lamdage22 on May 9, 2016, at 7:18:41
> So Venlafaxine is partially effective for me. Is this to be explained solely by Serotonin/Noradrenalin reuptake inhibition or does Venlafaxin have any other actions?
according to the binding affinity database, Venlafaxine only has notable binding affinities for SERT and NET.
here are the Ki values of 1000 and lower
http://kidbdev.med.unc.edu/databases/pdsp.php?knowID=0&kiKey=&receptorDD=&receptor=&speciesDD=&species=&sourcesDD=&source=&hotLigandDD=&hotLigand=&testLigandDD=&testFreeRadio=testFreeRadio&testLigand=venlafaxine&referenceDD=&reference=&KiGreater=&kiLessRadio=less&KiLess=1000&doQuery=Submit+Query
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poster:TriedEveryMedication
thread:1088804
URL: http://www.dr-bob.org/babble/20160501/msgs/1088816.html