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Re: amitriptyline and apathy? » B2chica

Posted by SLS on March 27, 2016, at 6:29:39

In reply to Re: amitriptyline and apathy? » linkadge, posted by B2chica on March 27, 2016, at 0:52:55

Hi B2C

I am curious as to why you are not using higher dosages of Pristiq and Topamax.

> Pristiq 50mg am
(100 mg/day)

> Topamax 25mg
(100-200 mg/day for depression)

> Amitriptyline 25mg
(50-100 mg/day - moderate depression)
(100-200 mg/day - severe depression)
(200-300 mg/day - rapid-metabolizer)


When someone responds robustly to a TCA, the improvement in depression tends to be global. Anhedonia should disappear along with with other symptoms. If it doesn't, you might do better with higher dosages of Pristiq.

Is it possible that amitriptyline is producing sedation that you are interpreting as apathy? For me, amitriptyline is a crappy medication. I feel a very yucky (medical term) sedation all day long, even after being on it for several weeks. Still, one is more likely to respond to amitriptyline than nortriptyline. Some people experience no daytime sedation at all, and still sleep well.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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