Posted by Hello321 on August 30, 2015, at 13:10:02
In reply to Re: Benefit of 5ht1a agonists - Oops » SLS, posted by SLS on August 30, 2015, at 12:50:31
http://www.ncbi.nlm.nih.gov/pubmed/9661257
Well, heres another study saying Flibanserin acts as a full agonist for 5ht1a receptors in certain areas of the brain and just a partial agonist at others, if i understand correctly. Then it says "Therefore, flibanserin presented a marked selectivity for postsynaptic 5-HT1A receptors when applied locally, but not when administered intravenously. It remains to be determined if flibanserin preferentially activates postsynaptic 5-HT1A receptors upon sustained systemic administration."
Uhh, what does that mean exactly? One has to take it a certain way for it to work at postsynapic receptors? Im guessing when taken by mouth, at least chronically, it does indeed agonoze the postsynaptic receptors.
poster:Hello321
thread:1081915
URL: http://www.dr-bob.org/babble/20150806/msgs/1081918.html