Posted by phidippus on August 19, 2015, at 21:26:09
Did Flibanserin fail to get FDA approval as an antidepressant? Flibanserin acts as a full agonist of the 5-HT1A receptor (Ki = 1 nM) and, with lower affinity, as an antagonist of the 5-HT2A receptor (Ki = 49 nM) and antagonist or very weak partial agonist of the D4 receptor (Ki = 424 nM). Nefazadone strikes as being very similar.
poster:phidippus
thread:1081532
URL: http://www.dr-bob.org/babble/20150806/msgs/1081532.html