Posted by ed_uk2010 on January 30, 2015, at 8:11:47
In reply to Re: Treatment of MAOI hypertensive crisis » ed_uk2010, posted by SLS on January 30, 2015, at 7:22:01
>I was hoping it would be approved so as to give me the option of carrying it around with me instead of nifedipine for MAOI hypertension.
Perhaps - but I'm unsure how helpful it would be to take phentolamine on top of prazosin. If you were to develop a severe hypertensive episode in spite of being on an alpha blocker already, nifedipine might in fact be more logical. Oral nifedipine is very rapidly absorbed from the capsules when swallowed whole. There is no need to chew, puncture or attempt S/L administration of the caps.
>It proved ineffective for ED.
I believe alpha blockers are effective when injected directly into the corpus cavernosum, but not systemically.
>Even chlorpromazine is used in emergencies.I've never felt convinced that chlorpromazine is a logical choice. It's thought that chlorpromazine exerts a hypotensive effect by acting as an alpha-1 antagonist, rather like prazosin. I think a selective alpha-1 antagonist would cause fewer adverse effects. Dopamine antagonists might reduce the nausea and headache however...
poster:ed_uk2010
thread:1075710
URL: http://www.dr-bob.org/babble/20150129/msgs/1075776.html