Posted by ed_uk2010 on January 29, 2015, at 13:19:18
In reply to Re: Treatment of MAOI hypertensive crisis, posted by SLS on January 29, 2015, at 12:55:22
>If nifedipine has already been taken, I'm not sure phentolamine is an option.
Even if phenolamine was available, it probably wouldn't be available in time....
Alpha blockers (doxazosin etc) and calcium channel blockers are often used together in chronic hypertension. There doesn't seem to be any specific interaction. Phentolamine, a non-selective alpha blocker, didn't have much place in most forms of acute hypertension because it caused too much tachycardia. Unlike phentolamine, alpha-1 selective antihypertensives such as prazosin and doxazosin don't normally cause tachycardia.
Considering the amount of prazosin you take, I wonder whether it would take more than the usual amount of tyramine to induce hypertension? I'm not suggesting you perform an experiment!
poster:ed_uk2010
thread:1075710
URL: http://www.dr-bob.org/babble/20150129/msgs/1075717.html