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Re: Multiple mechanism with Zyprexa and some atyp » Lamdage22

Posted by ed_uk2010 on January 27, 2015, at 5:56:40

In reply to Re: Multiple mechanism with Zyprexa and some atyp, posted by Lamdage22 on January 27, 2015, at 3:00:09

Morning.

> My mood is like a 4 out of 10.

It does sound like you need further treatment for this. Which antidepressants have you tried and how do you respond? It looks like you don't tolerate high doses of serotonergic drugs like venlafaxine.

>I could sleep yesterday with 40 mg pipamperone and 12.5 Zyprexa (instead of 15).

Excellent that you could sleep!

I suppose what I'm wondering is..... taking pipamperone may allow you to reduce Zyprexa to some extent by blocking some of the same receptors, but do you think things will be better by taking three antipsychotics instead of two? What do you plan here? The incidence of side effects with pipamperone does not seem very well established but sexual dysfunction/libido loss is often reported so I assume it elevates prolactin.

Regarding Seroquel, do you find you need the daytime doses to relieve agitation?

>Lithium at 300 led to humongous weight gain so i dont even want to know about, say 900.

You may need to be cautious about valproic acid (valproate) since it causes weight gain so frequently. It's generally more effective against manic symptoms than depression. Do you have a history of mania or mixed states? I'm wondering if this is why your doctor mentioned it.

 

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