Posted by SLS on January 16, 2015, at 2:10:03
In reply to Re: Abilify + other APs, posted by Christ_empowered on January 15, 2015, at 19:30:35
> > Would propranolol be of any help?
> Perhaps, but I can't say I rate it highly overall. A few people seem to respond really well though. C_E seems to do quite well with PRN risperidone so I'm not sure there's much reason for him to change. Another choice would be lorazepam 1mg, or 2mg if needed.
>
> >I had another thought: add Saphris (asenapine) and then taper/discontinue the Abilify.
>
> I get the impression Abilify has treated C_E very well though, apart from occasional breakthrough symptoms. I think switching to something else entirely would represent a risk. That's why I like the idea of sticking with in and just optimising the PRNs if needed.
>
> What do you think C_E?That's a reasonable question.
The question I have for you C_E is why have you, on numerous occasions, discontinued or reduced your dosage of Abilify until you ultimately relapsed? What have you been unhappy with?
Do you experience paranoia when you are ill?
I don't like the idea of treating the side effects of one AP by adding another, although that might be the only option available. It may be that Abilify is not such a great drug with which to treat schizoid psychoses and paranoid delusions, and can actually reduce the effectiveness of other antipsychotics, particularly those with low binding affinities. I believe this is because it out-competes drugs like Seroquel for binding sites and acts too much like an agonist.
Ed makes a great deal of sense. His ideas will provide adequate, if not familiar results. Personally, if I were inclined to look for something better, I would do the Saphris thing and simply add it to the Abilify and avoid the Risperdal. Depending on your results, you could then attempt to reduce the dosage of Abilify. I won't guarantee anything, of course. After all, this is medicine, not rocket science. However, I know one person who was able to cut her dosage of Seroquel in half after she discontinued Abilify. She was able to lose all of her Abilify-induced extra body weight once she added Saphris. I don't know how typical this is.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1075107
URL: http://www.dr-bob.org/babble/20150102/msgs/1075140.html