Posted by ed_uk2010 on January 14, 2015, at 1:04:21
In reply to Abilify + other APs, posted by Christ_empowered on January 13, 2015, at 18:34:30
>...anyway, I was wondering...is there a point in mixing Abilify with other APs, like I do when I take a little bit (2mgs-4mgs) risperidone on top? I mean, yeah, it works, more for agitation than anything else, but...
Considering your high dose of Abilify, I expect that taking additional antipsychotics on a regular basis would not be very helpful. Due to the high potency of risperidone, it may be able to displace aripiprazole temporarily (at the receptor level) when you take a PRN dose and act as a full D2 antagonist to reduce agitation. Its actions at 5-HT2 receptors may also be helpful for this purpose.
>would I be better off just taking a non-neuroleptic sedative?
You could alternatively use a PRN benzo, but only if you find that strategy effective. If you find risperidone effective as a PRN I don't see any particular reason to switch to anything else.
>
> ...its not my doc's long term strategy. Its a tolerable PRN thing. With all those D2 receptors "occupied" or whatever by the Abilify, would I be better off just taking a non-neuroleptic sedative?
poster:ed_uk2010
thread:1075107
URL: http://www.dr-bob.org/babble/20150102/msgs/1075116.html