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Re: lithium and inositol » mogger

Posted by mogger on January 1, 2015, at 22:08:26

In reply to Re: lithium dosing question (controlled release) » SLS, posted by mogger on December 31, 2014, at 15:04:38

Scott,

I have one question if you don't mind answering and then I promise I will stop bothering you! When I started 6 years ago inositol my libido dropped adding to all this. I noticed that lithium increases the amount of inositol in the brain? I could be reading the excerpt wrong below but just wonder your thoughts on it. It is from wikipedia. Thanks Scott,

Joseph

"Lithium treatment has been found to inhibit the enzyme inositol monophosphatase, leading to higher levels of inositol triphosphate.[63] This effect was enhanced further with an inositol triphosphate reuptake inhibitor. Inositol disruptions have been linked to memory impairment and depression.
In 2014, it was proposed that lithium treatment works by affecting calcium signaling by antagonizing N-methyl-d-aspartate (NMDA) receptors and inhibing inositol monophosphatase (IMP) to synergistically block the inflow of calcium into neurons from both external and internal calcium stores.[64]"


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URL: http://www.dr-bob.org/babble/20141120/msgs/1074700.html