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Re: lithium dosing question (controlled release) » mogger

Posted by SLS on December 30, 2014, at 23:05:37

In reply to Re: lithium dosing question (controlled release) » SLS, posted by mogger on December 30, 2014, at 20:33:59

> The way I would clearly know is the return of a plummet in mood. What it is doing is keeping my mood stable instead of being unipolar depression. I have no mania never have just ocd and depression. I suppose I shall have to wait and see won't I. Hopeful to hear you say .8 might be ok. I am on day 4 of 1200mg from 1500mg. Slight dip in mood but maybe withdrawals that will even out? Haven't felt withdrawals from lithium before so don't know what to expect. Thanks Scott,
>
> Joseph


Hi Joseph.

I am unclear as to what drugs you are currently taking.

It is possible that your brain needs a day or two to adjust. You can always resume 1500 mg/day if you continue to deteriorate. Have a little patience, though. Perhaps you lie somewhere along the bipolar spectrum. Did you ever rapid-cycle? When was the last time that you felt well? At what age did you first get depressed? Was there any anxiety?

There was some work done 10 or more years ago at Harvard / Massachusetts General reporting the use of low-dosage lithium in the treatment of unipolar depression. The study group found that lithium at dosages of 300 - 600 mg/day were effective when used to augment antidepressants. Most people settled on 450 mg/day. I don't know of any such studies of lithium when used as monotherapy.

I might try to lower my dosage of lithium from 450 mg/day to 300 mg/day in order to see if I feel more motivated at the lower dosage. I want to get a blood level first, though.


- Scott


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