Posted by SLS on December 31, 2014, at 23:31:18
In reply to Amisulpride for bipolar depression ?, posted by Chinaboy on December 31, 2014, at 22:32:59
> Once read from Internet that Amisulpride is a useful add-on treatment of bipolar I at a dosage ranging between 200-800Mg.
>
> Based on the thoery that it is a dopamine agonist at 50-300mg, I feel it might help with bipolar depression?
>
> Thoughts?I think the dosage range for amisulpride in the treatment of depression or dysthymia is 25 - 100 mg/day. Amisulpride is a dopamine antagonist that is preferential to presynaptic autoreceptors at low dosages. Blocking these receptors ends up being pro-dopaminergic because it signals the neuron to manufacture and release more dopamine via a negative feedback loop.
If you decide to try amisulpride, I would be grateful if you would report your results.
Thanks.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1074654
URL: http://www.dr-bob.org/babble/20141120/msgs/1074656.html