Posted by phidippus on November 10, 2014, at 18:20:41
In reply to Campral: NMDA antagonist, Glutamate Modulator..., posted by mogger on November 6, 2014, at 21:59:53
> Lamictal is a solid piece of my medication cocktail.
I hate to bring this up but some case studies show Lamictal worsens OCD symptoms in patients who are also bipolar.
>I am on 3 anti depressants, buspar 90mg, zoloft 150mg and remeron 60mg and am a non responder.
You're on more than enough antidepressants to combat the OCD effectively. Perhaps you need to try different antidepressants.
>my ocd/depression is a result of excitatory neurotransmitters needing to be quelled rather than a depletion of neurotransmitters
Its probably a case of both.
>ocd/anxiety came first and the depression was a by product.
Than you need to focus on getting the OCD under control.
1. Add a low dose of an atypical antipsychotic - there is often an excess of dopamine in the nucleus accumbens of OCD sufferers.
2. Add a glutamate antagonist - Topomax, Keppra, Lyrica, Gabapentin, etc. Riluzole is a glutamate antagonist.
3. There are other medicines which have shown efficacy in treating OCD: dextroamphetamine, Pindolol, Ondansetron, etc.
Campral was effective for general anxiety but didn't help much with my OCD. It did cause me depression-its a gaba a agonist which tend to carry the side effect ofg depression.
Eric
poster:phidippus
thread:1073254
URL: http://www.dr-bob.org/babble/20141017/msgs/1073336.html