Posted by ed_uk2010 on August 19, 2014, at 13:41:11
In reply to Re: Sertraline immediately eliminated suicide thoughts, posted by Lamdage22 on August 19, 2014, at 11:00:11
>I don't think i abandoned sertraline prematurely.
Did the restlessness happen even at low dose eg. 25mg or did you not try?
>Sertraline is a sigma 1 antagonist though and Fluvoxamine an agonist.
Both drugs are ligands at sigma-1 receptors, but as far as I know, the definition of what constitutes an antagonist vs an agonist at this class of receptors is very poorly understood as present. It may be that fluvoxamine is worth a try but you'd need to check for drug interactions with your other medication. What are you currently taking?
poster:ed_uk2010
thread:1069951
URL: http://www.dr-bob.org/babble/20140815/msgs/1070014.html