Posted by LouisianaSportsman on May 5, 2014, at 22:54:19
In reply to Re: Luvox CR, posted by rjlockhart37 on May 5, 2014, at 19:33:18
<your on brintellix, my personal thing...prozac does <increase amphatmine's effect
<Micromedex does confirm that Prozax does increase amphetamine's effect.
Micromedex, which is a drug interactions checker which is professional and you have to pay for, does also give a warning with Brintellix; however, it does not give a warning with Zoloft, Luvox, Lexapro, Paxil or even mirtazapine. Weird.
Micromedex:
Dextroamphetamine Sulfate (Dexedrine) : Vortioxetine Hydrobromide (Brintellix)
Severity: Major
Onset: Not Specified
Documentation: FairInteraction Effect:
Concurrent use of VORTIOXETINE and SEROTONERGIC AGENTS may result in an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes).Clinical Management:
Concomitant use of vortioxetine with serotonergic agents may increase the risk for serotonin syndrome and should be undertaken with caution. If concomitant use of vortioxetine with a serotonergic agent is clinically warranted, close monitoring of the patient is recommended, particularly during treatment initiation and dosage increases. If serotonin syndrome develops, discontinue vortioxetine and concomitant serotonergic agents and initiate supportive care (Prod Info BRINTELLIX oral tablets, 2013).Probable Mechanism:
additive serotonergic effects
poster:LouisianaSportsman
thread:1065262
URL: http://www.dr-bob.org/babble/20140419/msgs/1065285.html