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Re: Sudden sensitivity to SSRIs/side effects? » LouisianaSportsman

Posted by phidippus on March 4, 2014, at 1:43:44

In reply to Re: Sudden sensitivity to SSRIs/side effects?, posted by LouisianaSportsman on March 3, 2014, at 21:02:20

>"no AP without AD" philosophy you have, Eric.

Philosophy? Any prescribing psychiatrist worth his salt knows this as common knowledge. Why, even Wikipedia warns against.

>the 5-HT2A antagonism which is balanced out by 5-HT1a partial agonism

I don't think thats how it works.

> Lurasidone also has less of a cognitive imprint with its D2 receptor blockade pattern

The target of dopamine antagonism in OCDis the nucleus accumbens, which has a higher density of D1 and D3 receptors.

Eric


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