Posted by kavinsky99 on February 27, 2014, at 6:53:15
In reply to Re: Advice on which medication is best for my case » kavinsky99, posted by phidippus on February 26, 2014, at 22:41:42
> >I wouldn't say they're racing thoughts, just repetitive, relentless and extremely attention draining. Everything feels like second-priority compared to them, according to my brain.
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> You can't distract?
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More brain activity = more bad thoughts. Distractions are worse.> > They're unpleasant in nature, mostly based on memories of bad things that happened and ruminations regarding them.
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> Therapy is going to help you most with this issue.
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Therapy is likely to increase it, since most of my problems stems from being forced into therapy and the bad experiences associated with it.
Right now my mind is blasting angry thoughts at my last therapist (who was a crook), imagining what to say at the audience we'll have when the licensing board finds the time. (Can't sue this one. No evidence to show.)> > I don't cope. I literally just try to not think.
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> How's that working out?
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Better than anything. If I *try* to do something about it, I'm just feeding/agreeing with people in my head and it makes me feel worse, opening a cascade of bad thoughts.> >Other activites or "distractions" seem to actually worsen them.
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> Why do you think that is?
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As I said earlier, i'm guessing brain activity in general makes it worse. Anything that makes me think or stimulates me, worsens them. Staying still trying not to think is the best thing next to meds.
> > For depressed, anxious and bipolar people, is dopamine suppression the key-effect for the benefits received from APs?
>
> Well, schizophrenics benfit from the dopamine antagonism and certain seraotonin antagonism. While bipolar folk get the best benefit from seratonin antagonism as well as the dopamine antagonism. But now a days, a lot of the atypicals feature 5ht1a agonism, whicch helps with depression.
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Even a little dopamine antagonism makes me worse regarding ADHD symptoms, apathy and lack of motivation. Very low doses of APs and moderate doses of SSRIs are sure to cause it.
> > I wish I could try the norepinephrine ones first... I suffer from really bad nerve pain on my spine. Don't know if that worsens anxiety and OCD, though.
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> You and me both. I've never tried something that boosts norepenephrine.
>
I've used mirtazapine. Releases norepinephrine
instead of causing reuptake, so it's not good for pain. However, it's great for mood and motivation.
Reuptakers are going to be my next attempt. Either a pure NRI or a norepinephrine targetting TCA.> >By the way, benzos usually make me very agressive and depressed.
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> this is called a paradoxical effect. happens to me with certain benzos as well - Xanax is the worst. Last time I took it I had full blown ideations of bashing my son's head in.
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Yeah. Each benzos has it's own flavor regarding that. Lexotanil (bromazepam) seems to be the one benzo that is more likely to cause good feelings, according to myself and other people from forums.
Xanax and Klonopin seem to have bad depressive rebounds for a lot of people.> > What kind of side effects you had it on it?
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> Some sedation. Sometimes a depressed mood.
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> > Why is it important to have a serotonergic antidepressant on board?
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> When you have OCD, their are depletions of serotonin in certain parts of the brain. If you take an AP, those depletions worsen, making symptoms worse. Treating OCD with a serotogenic drug corrects the serotonine imbalance in the brain, easing the symptoms of OCD. Often, dopaminergic transmission is defective in the brains of people with OCD resulting in a surplus of dopamine. That's why APs are also used to treat OCD-the trick being that if you use too much AP, too much serotonin gets antagonized and symptoms worsen. Just enough AP corrects dopamine levels.
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Never made a connection to the serotonin antagonism from APs and how I feel awfully depressed with them. True, the antagonism outweighs the agonism.One day I might try low dose APS again. 0.25mg risperdal wasn't so bad.
My next step is to stabilize tianeptine. Then I'm going to try out supplements before more medication. What are your thoughts on supplements? I'm trying to look for something less invasive than / good add-on to medication.
By supplements I mean isolated aminoacids, herbal extracts, etc..> >Thought APs usually had serotonergic properties of their own.
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> They antagonize way more serotonine receptors than they agonize.
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> >Honestly, therapy retraumatizes me even subconsciouslly.
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> That's kind of the point of therapy with OCD - ERP (exposure and ritual prevention). You are exposed to the thing that causes you anxiety systematically until it no longer causes you anxiety.
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Not the reason, though. I truly *HATE* the whole concept. Maybe from being exposed to such a bad side of it, in awful ways. But honestly, I don't want nothing to do with it. It's important, more effective and healthier to just manage on my own. Most of my intrusive thoughts are therapists and psychiatrists talking to me in my head.I don't remember if I mentioned on the original post, but I was forced on therapy my entire life. And man, even after becoming an adult and seeking on my own, my experiences with it were bad. I don't think Brazil has good schools forming competent, ethical therapists. It's amazing the ammount of crazy people (not really crazy, as in having a psychiatrical disorder. that wouldn't be bad. More in being maladjusted, weird, unhappy, unethical, etc..).
If I ever feel inclined to learn about it, I'll just study it on my own. CBT/DBT seems interesting.
> Eric
poster:kavinsky99
thread:1060760
URL: http://www.dr-bob.org/babble/20140214/msgs/1061436.html