Posted by Emme_V2 on January 10, 2014, at 18:33:38
In reply to Re: minocycline » Emme_V2, posted by bleauberry on January 10, 2014, at 9:16:19
> Emme that's awesome! Glad to hear it.
Thanks! I was pretty amazed at the success - there really isn't a lot of clinical experience with this drug for psychiatric indications, although there are several trials for different disorders. But my pdoc was open to giving it a try, and we hit pay dirt. After some startup stimulation, which subsided, it feels like a very clean antidepressant for me.
> I am obviously not the expert on minocycline in particular but I am happy to hear of the things about it that I did not know. The glutamate angle, I did not know that. Your response to the drug....awesome! Love it.Yeah, me too. :) If I were a pharmaceutical company, I'd be trying to figure if it's possible to separate out the antibiotic properties of this drug from the other capabilities it has and formulate a new drug.
> Thanks for sharing. If I ever go back to revisit the tetracyclines, I might just give that one another try. I was so infected when I first tried Mino, it was like a nuclear bomb to me, massive Herxheimer reactions, terrifying. I believe I could probably handle it now without much problem in the Herx department.
Yeah, if you've got Lyme on board, I imagine it's a bit of a different ball game in terms of how to dose and what you can tolerate. I've known a couple of people who have taken mino for Lyme, and they had to feel their way with it.
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> > > Just curious. Why are folks singling out minocycline as the antibiotic to take? There are lots of choices. Why that one?
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> > The nationally-recognized psychopharmacologist who suggested I try minocycline did so because of its action on the glutamate system - totally unrelated to its antibiotic properties. I am NOT taking minocycline as an antibiotic. I take it as a psychotropic medication, and it is a very effective one for me.
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> > A 2004 article by Pae et al. (do a search on Pubmed) describes all the different ways in which minocycline could have antidepressant effect - unrelated to its antibiotic properties. This is an interesting drug.
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poster:Emme_V2
thread:1058144
URL: http://www.dr-bob.org/babble/20140104/msgs/1058219.html