Posted by SLS on October 12, 2013, at 18:33:16
In reply to Re: Parnate (tranylcypromine) failure?, posted by Snell on October 12, 2013, at 17:49:50
> Thank you all for your considered replies. I had some relief, and then when my pdoc insisted that I reduce to 30mg, I began slipping, slipping, slipping. Now I'm fully and completely depressed, with all the symptoms except suicidality. I told my pdoc that I thought his experiment was a failure, and that either (a) I must require a higher dose or (b) some augmentation strategy. I can't tell you how disappointing this is to me. I feel that I worked really hard to get here. The only other psych med that I'm on, now, is Lamictal 100mg. I feel that so many people's response to this medicine is that they're riding the tail of a comet, and yet here I am in my crypt again. I am very dispirited.
>
> I'm in the United States, and here the "standard" dose is not 30mg but 20mg. But honestly, after 10 days at 30mg and watching my mood collapse, I can only come to the conclusion that some other modality, or approach, must be called for. I've come across several academic papers that advocate 1mg/kg. I weigh 100 kg, so you do the math. I'm not trying to die, Lord knows; I just want relief of this horrible pain.It is my observation that, with Parnate, the effective dosage range is 40 - 80 mg/day. The high-dosage strategy employs dosages of 120 mg/day and higher.
I was not aware of a 1 mg/kg formula for Parnate. I have seen it for Nardil, though.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1051793
URL: http://www.dr-bob.org/babble/20130930/msgs/1052088.html