Posted by SLS on January 20, 2013, at 6:24:22
In reply to Re: Clomipramine - Augmentation options? » CGDR2, posted by tensor on January 20, 2013, at 2:30:17
> I know fluvoxamine is used in combination with clomipramine, it makes clomipramine more serotonergic due to a metabolic change.
Hmm. Interesting. I didn't know that. You are right, of course.
Which metabolic route (enzyme) is responsible for this? I know that CYP3A4 is inhibited by fluvoxamine, but that should not affect a TCA, should it? Is clomipramine different than the other TCAs in this regard?
I hope you slept well.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1035819
URL: http://www.dr-bob.org/babble/20130112/msgs/1035845.html