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Re: MAOI to SSRI, what is the avg washout, 7-10 days? » gilmourr

Posted by SLS on December 31, 2012, at 22:49:50

In reply to MAOI to SSRI, what is the avg washout, 7-10 days?, posted by gilmourr on December 31, 2012, at 17:18:13

> New combo. Came off Nardil.
>
> Just started 25 mg of Lamictal.
>
> I need info on ppl that have discontinued a MAOI and added a SSRI. How long did you wait? I know I got away with a 10 day wash out without having any serotonin syndrome issues.
>
> This time I want to start after a 7 day wash out because the whole 14 day washout is kinda ridiculous.

I think "ridiculous" is a rather strong word for exercising caution in the face of uncertainty.

> What is the earliest you've gotten away with switching from a MAOI to SSRI?

If I or someone else were to tell you that waiting two days was sufficient, how would that affect your decision-making process? Would that convince you to wait only two days?

I never tried two days. The reason I never tried two days was because it can take as long as two weeks for the recovery of MAO activity. It takes that long for the body to synthesis new enzymes.

7 days? 10 days?

I don't know what would be safe for you given your individual biology. I just think that you should not make the mistake of taking my word for it. If the 3 days is that important to you, then take the next 7 days to do more research.

I wait 14 days. But that's just me.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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