Posted by SLS on December 20, 2012, at 14:44:32
In reply to @ Scott, posted by Lamdage22 on December 20, 2012, at 13:41:30
Are you bipolar?
Have you ever experienced mania?
What are you taking right now, and at what dosages?
> Geodom + 20mg Parnate seemS to give me serotonin syndrome symptoms.
>
> SNRI with MAOI = absolute no go.You are absolutely right. That's why I won't combine Geodon with a MAOI. Although it is an antipsychotic, Geodon also has SNRI effects.
> Scott, whats the lowest abilify dosage you have seen effective for stabilizing
2.5 mg/day for depression
10.0 mg/day for bipolar mania.> and what weight effects are to expect from that dosage?
I am not convinced that Abilify-induced weight gain is dosage-dependant.
Some people do gain weight with very low dosages. However, given the potential therapeutic value of Abilify, I would consider trying it and see if weight gain does occur. You can always stop taking it if you don't like how it affects you.
> Also: Would Lamictal 125 mg and lithium xr in 100mg augment eachother in stabilizing?
The NIMH used to employ that combination, especially for rapid-cycling presentations. Your dosages of Lamictal and lithium are a bit low, though - even for unipolar depression. What happens when you increase Lamictal to 200 mg/day or lithium to 300 mg/day?
I have seen the following combinations work. They can even be combined with Parnate.
Wellbutrin + Lamictal
Abilify + Lamictal
lithium + Lamictal
nortriptyline + LamictalIt might be interesting to combine Wellbutrin, Lamictal, and Abilify.
> I can absolutely not take weight gain sides for medical reasons. Most likely candidiasis.
I understand.
What is it about weight-gain that acts to exacerbate candidiasis?
Some people gain weight from lithium alone, but I don't know how it affects blood lipids or blood glucose.
The antipsychotic, Latuda (lurasidone) is being studied for depression with good results. Like its chemical cousin, Geodon, it is supposed to be weight-neutral. Unlike Geodon, it is not an SNRI and should not produce serotonin syndrome. I have tried Latuda. I believe I was taking Parnate at the time. I don't recall it helping. Everyone is different, though.
Just to throw the idea out there, minocycline is an antibiotic with additional properties which are unrelated to infections. Among these unrelated properties are anti-glutamatergic and anti-inflammatory effects. These are thought to produce benefits in treating depression. I have reason to believe that minocycline may be particularly useful for people who have responded to Wellbutrin, Lamictal, or Abilify.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:499503
URL: http://www.dr-bob.org/babble/20121217/msgs/1033394.html