Posted by sk85 on November 10, 2012, at 13:33:53
In reply to Re: How to battle anticholinergic amnesia? » sk85, posted by SLS on November 9, 2012, at 15:50:00
> > Well I'm back on clomipramine. It just works so well for a lot of things that are going on in my life, from dystonia to OCD. But it really affects my memory - a reason why I have discontinued it before on numerous occasions as my work involves remembering a lot of things. However, for the sake of my emotional and physical wellbeing I guess I'm going to have to sacrifice something. No silver bullet for me.
> > Still, has anyone tried to take anything for their cognition when on tricyclics or other anticholinergic medication? I'm looking for real experiences. I've tried some supps (phosphatidylserine, low dose piracetam, choline) but they aren't that effective, or maybe I haven't found the right one.
> >
> > -Ikaros
>
>
> Sorry, Ikaros. I don't have any personal experience with the following agents:
>
> Cholinesterase inhibitors like Aricept (donepezil)?
>
> Pilocarpine? I mention this drug only because it is an acetylcholine muscarinic receptor agonist. I don't know if it has ever been used to remediate anticholinergic cognitive side effects. Perhaps it is worth a quick look.
>
>
> - ScottPilocarpine has the potential to induce epilepsy, so I'd rather not go there.
Aricept is interesting. But has anyone not suffering Alzheimer's taken it and found it useful? Cholinesterase inhibitors can have on their own right numerous SEs.
A more interesting question would be, does tolerance develop to the anticholinergic effects, or is this a false hope?
poster:sk85
thread:1030937
URL: http://www.dr-bob.org/babble/20121029/msgs/1031015.html