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Re: question about tardive dyskinesia pathophysiology

Posted by neuroscience on October 26, 2012, at 8:05:46

In reply to Re: question about tardive dyskinesia pathophysiology » neuroscience, posted by phidippus on October 25, 2012, at 21:36:56

> If they did not elaborate on the inconsistencies, it would be hard to postulate exactly what they were.
>
> What did you think about my idea of treating with Keppra?
>
> Eric

Keppra seems promising like Nootropyl is. I believe its use was based on the neurotoxic hypothesis. Dopamine receptor blockade leads to an increase of dopamine turnover thus producing excessive free oxyradicals that damage striatal neurons.

My original question has to do with the hypothesis that TD is caused by an alteration of sensitivity and number of dopamine receptors.


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