Posted by Lou Pilder on October 25, 2012, at 15:38:25
In reply to question about tardive dyskinesia pathophysiology, posted by neuroscience on October 25, 2012, at 13:35:55
> I'm reading a book called Neurology for the Non-Neurologist (6th Edition), and on page 281 it talks about TD pathophysiology and says:
>
> "Although choreiform movements may begin when the neuroleptic is chronically administered without a change in dose, the most common clinical setting in which the movement disorder emerges is after the dose is lowered or discontinued. This latter setting is in keeping with the postulate of lowering the pharmacologic blockade of the dopamine receptor and allowing normal dopaminergic mechanisms to resume their interaction with the already hypersensitized receptor. Although there is much evidence in animal models to support this notion, there have been inconsistencies."
>
> My question is: what inconsistencies?neuro,
The reason fo the inconsistancies is that the cause of TD is much more than what they think.
Let us go to tobacco smoking. Not all smokers get lung cancer, and some non-smokers get lung cancer. Causality is a long involved process to determine sometimes in relation to this. Some people get TD in the first week as akethisia. Some years later or not at all. But there is a causality relationship with the drug and TD. But corrolation does not prove causality.
It has been reveald to me what causes these movement conditions as a result of taking mind-altering drugs. And it has been revealed to me healing. This healing I am not permitted to post here due to prohibitons to me by Mr Hsiung. It involves the foundation of Judaism as revealed to me. There could be people here to tell you to use human acheivement in relation to taking more drugs and they are permitted to do so even though the condition is induced by a drug. I know of cases healed by divine accomplishment. Look at the admin board here and a member calls this B*llsh*t and says that I believe it. Sadly. Mr Hsiung to this day alllows defamation to be posted to me including insulting Judaism and Islam and other faiths. This could keep you from having dialog with me, yet it is allowed here.
Lou
poster:Lou Pilder
thread:1029742
URL: http://www.dr-bob.org/babble/20121018/msgs/1029754.html