Re: Pristiq dosages of 200 - 400 mg/day. » SLS

Posted by phidippus on September 5, 2012, at 14:28:13

In reply to Re: Pristiq dosages of 200 - 400 mg/day. » phidippus, posted by SLS on September 5, 2012, at 8:33:40

Effexor works as an SNDRI at high doses, so not only does it affect reuptake of seratonin and norepenephrine, it blocks reuptake of dopamine, allowing more dopamine in the system.
Wellbutrin inhibits reuptake of norepenephrine and dopamine, so it might work synergestically with the Effexor, or you may get too much norepenephrine and dopamine acting on the CNS-I don't know what effects this would cause.
Lamictal will of course help keep your mood stable while taking the above mentioned antidepressants, however I can't speculate on how it will react with Effexor and Wellbutrin.
What are you currently taking?
Eric

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