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Re: going off meds - finding doc for opiods or stims? » g_g_g_unit

Posted by novelagent on June 21, 2012, at 14:24:58

In reply to Re: going off meds - finding doc for opiods or stims? » novelagent, posted by g_g_g_unit on June 21, 2012, at 0:40:42

Having been on memantine and amphetamine myself, I know it does make the amphetamine more effective, but it does not do so by "affecting tolerance." I never have developed any tolerance fo amphetamine. I think they are conflating tolerance with potentiation,

I've also been on aricept and amphetamine, which also potentiates each other. I couldn't take more than 5mg of aricept, even though 5mg is only suppose to be used as a starting dose before going to 10mg. So it's just potentiation, not "tolerance" being affected.

Tolerance is rare on amphetamine at therapeutic doses-- but on the Internet, people think it's "tolerance" when the same dose doesn't make one feel super awesome while doing boring tasks like day one. That's not tolerance-- that's an issue with unrealistic expctations for a drug.

> > memantine doesn't do anything for tolerance. >Forums have posts about memantine "reverse >tolerance" by people (not you) who misread the >term "reverse tolerance" to mean "reverses >toleramce" and that's where you're getting that >from. If you ask me, it's mostly written by >people who take excessive amounts of >amphetamines-- enough to cause tolerance- and >their IQ is impaired... they also (not you) get >obsessive on those forums about it, since >they're hyperfocused.
> >
>
> There's more than enough anecdotal evidence to suggest that it does. If you look up the gigantic Memantine thread on addforums, you'll find a poster called surferdude who's been on the combination for more than two years. He's also either currently in med school, or a graduate (I forget the exact details) and is interning at a hospital, so I doubt his IQ is impaired.


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URL: http://www.dr-bob.org/babble/20120608/msgs/1020005.html