Posted by bleauberry on June 15, 2012, at 8:02:20
In reply to Boring reality...no dopamine release, posted by rjlockhart04-08 on June 11, 2012, at 1:45:25
I don't know, in my own journeys I have discovered that norepinephrine is just as big a player in the pleasure department as dopamine is. I think they work in concert. If one is a bit off, the whole team suffers. It isn't just one or other. It isn't just dopamine.
Savella is the only thing I've ever tried that seemed to wake the pleasure department pretty good without numbing things down....anti-anhedonia even after ECT failure! That's pretty good for any med. Also sort of close in the same way was low dose nortriptyline with low dose zoloft. Low dose Parnate also. It's hard to pindown exactly what chemistries we are dealing with, because it could be ritalin or vicodan that livens up the pleasure department on one day but not another day.
Your combo of prozac and zyprexa is actually pretty potent at boosting brain firing of dopamine and norepinephrine. I think a problem may be though that a lot of it is being blunted by the high dose of prozac and being blunted by the blocking of dopamine receptors by high dose zyprexa. The other meds except nuvagil are probably making it worse too.
If you are satisfied for the time being with how your meds are working overall, except for the pleasure thing, then my guess is the straightest way to get the pleasure department going is with either a higher dose of nuvagil or ritalin.
> I don't know how many times I've read but when we feel alive...its vary crude awnser but usally dopamine is envolved, when we have a successful way to make money...when we eat fav food and enjoy it, maybe some of us even enjoy wine and beer....its all directed toward the pleasure systems in our brain...if we had no dopamine release...we would not love the things that we do for pleasure. There's alot more indepth info on this...this is just a tiny view....but I've realized that I have lost my ability to expierience life and pleasure...nothing makes me feel like im alive unless I use methamphetamine, cocaine occastionally....but theirs got to be a reason why this happening...I can't just rely on substances to let me feel normal...there got to be some other way to fix this without medication. I know the first thought is ECT..wouldnt mind it, but its the last resort. Like i've thought about changing my belief and thought structures to diffrent aspects to see reality diffrent.
>
> I'm awnsering my own post, but im asking who ever reads this...i feel trapped in this grey thinking of numb to get away from radiating pain of failure.
> anyone?
>
poster:bleauberry
thread:1019562
URL: http://www.dr-bob.org/babble/20120608/msgs/1019764.html