Posted by SLS on March 10, 2012, at 14:47:34
In reply to New med advice? (sorry, long post!), posted by kagome on March 10, 2012, at 10:30:43
Just a few ideas for the augmentation of Parnate:
1. Abilify 2-5 mg/day
2. lithium 300-600 mg/day
3. Nortriptyline 75 mg/dayI am currently have success with the following treatment regime:
Parnate 80 mg
nortriptyline 150 mg
Lamictal 200 mg
Abilify 10 mg
lithium 300 mg
prazosin 6 mgPrazosin is an interesting drug. It has made me respond much better to the other drugs I take. Prazosin is an old drug originally indicated for hypertension. It enters the brain readily and blocks NE alpha-1a/b/d receptors. It has recently been discovered to help in the treatment of post traumatic stress disorder (PTSD). I'm sure it will help some people with treatment resistant depression (TRD). I don't yet know what case profiles make the best candidates for prazosin augmentation. My first inclination is to guess that people who have a history of childhood physical abuse, emotional abuse, or neglect would be helped with prazosin, as these things can produce a form of developmental PTSD that is without the classic adult PTSD symptoms. Perhaps developmental PTSD drives depression. At this point, the PTSD is obfuscated by depression and rendered virtually invisible. These are nothing more than thoughts that I am playing with.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1012720
URL: http://www.dr-bob.org/babble/20120302/msgs/1012730.html