Posted by SLS on February 9, 2012, at 6:59:20
In reply to Re: Does abilify work for anhedonia, posted by Tomatheus on February 9, 2012, at 2:42:31
> n_shrimpie,
>
> I take 5 mg of Abilify and have taken up to 10 mg of the medication, and I haven't noticed a reduction in the severity of my anhedonia since I've been on the drug. I don't know if Abilify might help others with anhedonia, but I just wanted to relate my experience with the medication as it relates to anhedonia.
>
> TomatheusI forgot to mention that I take antidepressants along with Abilify. Without antidepressants, I don't know if Abilify would help improve my anhedonia. Probably not. Abilify can work well with Lamictal if you are trying to avoid antidepressants.
Perhaps I exaggerate in my mind the positive effects that I think Abilify has on my anhedonia. However, Abilify is the only AP that acts to stimulate dopamine D2/D3 receptors as a partial agonist. D3 receptors in the nucleus accumbens are thought to mediate feelings of pleasure and reward. Currently, there is a new drug being investigated as an antidepressant that is, like Abilify, a D2/D3 partial agonist. Designated OPC-34712, this drugs is a product of Otsuka Pharmaceuticals, the developer of Abilify.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1009756
URL: http://www.dr-bob.org/babble/20120202/msgs/1009792.html