Posted by Chairman_MAO on October 10, 2011, at 7:40:39
In reply to Re: Quick summary on VIIBRYD so far?, posted by SLS on October 9, 2011, at 23:32:00
>If you react negatively to SRI drugs, perhaps you will react negatively to Viibryd.That's what happened to me. I really wanted to be "compliant", and I only even tried this thing because I am finally seeing the doctor that I absolutely trust again. I could not make it past day 10; the anxiety and dysphoria was so severe (despite being on 4mg clonazepam) that I was scared to raise the dose to 20mg. I also felt a sense of physical malaise. When SSRIs do "work" for me, I tend to just get a flat affect and my ADD is worsened (positive effect of psychostimulants attenuated). I put a call into him at day 10 telling him that I just couldn't take it, asking what should I do, and to please call me back. He never returned it. I just got his trust back enough to get my Dexedrine again and I am so scared of him viewing me as "non-compliant".
I just want Nardil or Marplan back like I used to have (with the Dexedrine). He wants me off of clonazepam. Fine, I'll do that (ugh), but I need something that actually works for my anxiety/agoraphobia. I do not have major depression.
Now I wish I never stopped taking Nardil, although it's been nice to lose 40lbs+.
> That is an educated guess established through association. I cannot tell you that I am sure that you will react negatively to Viibryd, so I will not tell you not to try it. I remain uncertain. I accept uncertainty. I embrace uncertainty. It gives me hope. It also prevents me from being too smart for my own good. By taking this stance, I agreed to try Viibryd at the recommendation of my doctor, despite my suspicion that drugs like gepirone (SRI + 5-HT1a partial agonist) were not robustly effective in treating depression.
That is exactly what I did. Everything I knew and had experienced said that this wouldn't work, but I took it because this guy is the only one I have access to who gives a damn, and I know he is competent. I tried it. I simply could not tolerate the dysphoria. You know that black box warning that says "may produce suicidal ideations"? Well, that's me. And it doesn't apply to MAOIs, just the SSRI drugs.I'm scared to tell him that because I don't know if that's the best way to get my MAOI + psychostimulant combination back. I've got the Dexedrine back, but he wanted me to try this first instead of an MAOI. I really want off the "med-go-round" because I've tried myriad SSRIs, a TCA, and 2 MAOIs. The primary problems are social phobia/agoraphobia and inattentive ADD. By far the best combination was d-amphetamine + phenelzine. I'd like to try Marplan instead because of the weight gain, but I'm wondering if I should just go back to Nardil anyway and try to watch my diet because Marplan might not be as effective.
I see him in two days. I am hoping that he's still willing to work with me, and it's become somewhat of an obsession. I do not have a lot of resources and this is by far the best doctor I have access to. There is no one else I have access to would would dare do things like touch an MAOI + psychostimulant combination (he is a professor of psychopharmacology at a medical school).
I'm trying to stay positive. If the titration pack allowed at starting at way lower doses and going up very slowly, I might ahve been able to tolerate it. But I'm not sure that the end result would have been anything to go wild about, because, as I said, the primary problem is anxiety/social phobia. With regard to the depressive spectrum, I am dysthymic. The psychostimulants are enough to help that along with the ADD.
I'm glad it's working out for you. I'm trying not to drive myself crazy thinking about this until Wednesday.
All the best.
poster:Chairman_MAO
thread:999263
URL: http://www.dr-bob.org/babble/20111006/msgs/999316.html