Posted by SLS on October 9, 2011, at 23:32:00
In reply to Re: Quick summary on VIIBRYD so far? » SLS, posted by Laney on October 9, 2011, at 22:55:05
> Scott,
>
> How would you compare it to Cymbalta or Effexor? I'm very happy it's had such a favorable response with you. I also hope this with Uncouth!
>
> LaneyFor ME, Viibryd is exerting a moderate antidepressant effect without producing those side effects commonly reported by people taking Effexor or Cymbalta. It is a very clean drug for ME. Time will tell if apathy or flat affect develop with this drug.
For Uncouth: Why does Viibryd treat depression effectively while a combination of buspirone and a SSRI does not? Why is gepirone not effective?
I am sure that scientists are coming closer to being able answer such questions definitively. I don't think they are there yet, though. I know that I am not.
I know I am being evasive and irritating, but I think it is important to recognize the difference between what we know and what we don't know. For now, we use empirical observations that yield educated guesses by establishing associations. The brain is still a black box when it comes to understanding mental illness and the physiology behind the therapeutic effects of psychotropic drugs. If you react negatively to SRI drugs, perhaps you will react negatively to Viibryd. That is an educated guess established through association. I cannot tell you that I am sure that you will react negatively to Viibryd, so I will not tell you not to try it. I remain uncertain. I accept uncertainty. I embrace uncertainty. It gives me hope. It also prevents me from being too smart for my own good. By taking this stance, I agreed to try Viibryd at the recommendation of my doctor, despite my suspicion that drugs like gepirone (SRI + 5-HT1a partial agonist) were not robustly effective in treating depression. It appears that I was wrong. I guess I can live with that.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:999263
URL: http://www.dr-bob.org/babble/20111006/msgs/999283.html