Posted by Phidippus on October 4, 2011, at 12:24:28
In reply to Re: Tramadol, Oleptro.. + LONG RANT WARNING » Phidippus, posted by uncouth on October 3, 2011, at 19:17:30
I used to be just like you. A brand new medication every 2 weeks or so. I've been on most of the anticonvulsants, all but one of the atypical antipsychotics, many, many ADs, stimulants and more off label meds than one could fathom.
One day, one of these meds is going to bite you in the *ss. I got NMS from Invega and nearly died. After that my lust for prescription medication waned. It may happen this way for you too. Or you may just end up dead.
One thing I might suggest for you is you try to strip all your meds down to just one you take regularly. I imagine for you it would be your mood stabilizer. Leave it alone and try other medications as you please. You need a rock, you sound like you're all over the place with your mood and your thinking.
"would appreciate hearing the reasons why you chose what you chose, especially those infrequelty used TCAs. what is special about clomipramine and amytriptaline? i may have tried clomiprmaine before but it was a long time ago and not for very long. it's super serotoniny right...but what else?"
I suggested the TCAs for your depressive swings. TCAs tend to not rock the boat like SSRIs. I take Clomipramine and it treats both my depressive swings and my OCD.
"do these TCA options sidestep the SSRI side effects that can occur like dopamine hypofunction and affective blunting and potentially amotivation, apathy, sexual issues?"
Affective blunting, apathy and amotivation have never been a problem for me while on the drug, however sexual dysnfuction has been a problem.
"whats the logic behind memantine?"
Glutamate antagonist can treat depression.
"is the logic here the same logic behind ketamine, or is there something else you think its doing?"
Ketamine is an NMDA antagonist and has been studied for its effects on depression.
tramadol - has been studied as a treatment for depression, OCD and anxiety. It is an weak SNRI and opiod agonist. It also acts as an NMDA antagonist. I took this medication and it treated my OCD very, as well as providing a mood lift.
buprenorphine-Trying to get my pcp to prescribe it'
naltrexone-Is an opioid antogonist. Not good for OCD.
tianeptine-Just because its foreign doesn't mean its better. Not for the bipolar.
disulfiram-The substance was intended to provide a remedy for parasitic infestations; however, workers testing the substance on themselves reported severe symptoms after alcohol consumption. What the hell would you do with this?
lamictal-Maybe you can stick to this one.
rilutek-I took this medication and experienced severe panic. Paradoxical effect?
ketamine-Good for depression and OCD. Just don't put yourself in a K-Hole.
psilocybin or lsd-At what does do you lose your mind?
zonegran-Has some data backing it as a mood stabilizer. Great for migraines. Great for getting stupid.
vyvanse-smooth mechanism of action, no buzzy stimulant feelings.
amantadine-First concocted as an anti-viral. Now used for a variety of purposes. Didn't do sh*t for me.
poster:Phidippus
thread:998639
URL: http://www.dr-bob.org/babble/20110925/msgs/998713.html