Posted by jono_in_adelaide on April 14, 2011, at 18:24:53
In reply to Re: Nortriptyline vs reboxetine, posted by mtdewcmu on April 14, 2011, at 11:23:44
Re Symbax,
I think it would have made a lot more sense for a combination drug for depression to have combined an SSRI (probably not fluoxetine however) with either bupropion, nortriptline or desipramine - hit both the seretonin and noradrenalin system, rather than giving people Prozac plus Thorazine
I know antipsychotics have a place (amitriptyline/perphenazine has been around for over 40 years) but realy, after a SSRI fails, a SSRI plus an NARI makes a lot more sense to me than an SSRI plus antipsychotic
Infact, there is probably a need for an assortment of combo meds
SSRI plus bupropion
SSRI plus Lithim
SSRI plus atypical antipsychotic
NARI plus atypical antipsychotic
etc
so that patients get an easy "one pill once a day" regimen but still have the benifits of combination therapy
poster:jono_in_adelaide
thread:981366
URL: http://www.dr-bob.org/babble/20110406/msgs/982842.html