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Re: It seems Ago + Prozac is the perfect match BUT...

Posted by desolationrower on April 5, 2011, at 21:28:16

In reply to It seems Ago + Prozac is the perfect match BUT..., posted by Agomelatinehope on April 5, 2011, at 7:07:48

> The Prozac dose I was taking was 10mg (half pill).
>
> From what I recall reading is that
> it only had 5HT2-C antagonistic qualities at lower doses so...

not sure which of the two drugs. But you need a highish dose of prozac/fluoxetine for the 5ht2c to be significant. The more of a drug you take, the more receptors/pumps it can interact with. And higher doses start to interact with receptors/pumps that it has less affinity for.

> Maybe that great feeling was the mixture of the 5HT2-C antagonistic
> qualities of Prozac (since it has such long life and I had stopped
> taking just before taking ago) + Ago itself.

this seems more likely.

> So, do you think it might be a good idea to take for instance, 5mg
> Prozac (1/4 pill) + Ago ? Would I get then that estimulating feeling
> on a daily basis?
>
> Thank you so much!

Maybe the benefit was taking the sri along with the agomelatine, which was significant enough of a 5ht2c antagonist. I think combining these drugs could work well. though you might want an sri with more hypnotic effect like fluvoxamine.

-d/r


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poster:desolationrower thread:982000
URL: http://www.dr-bob.org/babble/20110321/msgs/982042.html