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Re: Alpha-delta sleep and cymbalta?

Posted by desolationrower on March 30, 2011, at 12:02:17

In reply to Re: Alpha-delta sleep and cymbalta? » floatingbridge, posted by Christia on March 27, 2011, at 12:25:02

IN general, antidepressants improve sleep architecture. Problems with 'delta' or deep sleep are common in depression. Dreaming mostly occurs in REM, and excess REM occurs with depression. The rebound effect is an exaggeration of hte problem you had without the antidepressant.

Something like trazadone would be ok, except if you have problems with fatigue already, a long-half-life drug that is mostly sedative is probably going to make sleepiness worse.

It might be the sri effect of the cymbalta that is causing fatigue. Is it a lassitude and indifference?
I'd say switch from cymbalta to nortriptaline; it has less sri effect, and 5ht2 antagonism that also improve sleep architecture.

-d/r


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URL: http://www.dr-bob.org/babble/20110321/msgs/981463.html