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Re: Questions On Depression and Nardil » luckyduck

Posted by pedr on February 3, 2011, at 13:36:45

In reply to Re: Questions On Depression and Nardil, posted by luckyduck on January 25, 2011, at 18:19:44

Hi Zach,
do remember to take everyone's recommendations with a pinch of salt - YMMV. For instance, there is no research whatsoever on the body weight 1kg / 1mg ratio. It's a rule-of-thumb that some psychs employ but certainly not all. My (competent) psych had never heard of it.

That said, the very first reference on Nardil's wiki page -http://en.wikipedia.org/wiki/Phenelzine is the FDA labelling - http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011909s038lbl.pdf

which states, quote

DOSAGE AND ADMINISTRATION
Initial dose: The usual starting dose of NARDIL is one tablet (15 mg) three times a day.
Early phase treatment: Dosage should be increased to at least 60 mg per day at a fairly
rapid pace consistent with patient tolerance. It may be necessary to increase dosage up to
90 mg per day to obtain sufficient MAO inhibition. Many patients do not show a clinical
response until treatment at 60 mg has been continued for at least 4 weeks.
Maintenance dose: After maximum benefit from NARDIL is achieved, dosage should be
reduced slowly over several weeks. Maintenance dose may be as low as one tablet, 15
mg, a day or every other day, and should be continued for as long as is required.

-- end quote

So unfortunately you have some time yet before you'll know if it's going to have an effect for you. My personal recommendation is that you persevere since Nardil has a good track record of helping when all other meds have not. I had tried pretty much all the classes of med, including combo's, before Nardil and only Nardil has had a prolonged, robust effect on my depression & OCD. For the record I am on 90mg.

HTH,
Pete


Treatment Resistant depression, anxiety, OCD: 13 years
IBS-C & GERD: 8 years
Current meds: 90mg Nardil, 300mg Zantac, 20mg Prilosec


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