Posted by PeterJ on January 18, 2011, at 16:28:47
In reply to Re: How is testosterone connected to depression? » linkadge, posted by maya3 on January 16, 2011, at 12:38:55
> Does that mean that high testosterone raises dopamine levels?Not in all brain areas, but it does in the prefrontal cortex (at least for male rats):
http://cercor.oxfordjournals.org/content/21/1/222.long
I have been on testosterone treatment for 17 years and an activating effect is subjectively clear and related to my serum T level. This effect is increased by inhibitors of estradiol production such as anastrazole, which I recently started.
I could certainly see how too much T could exacerbate psychosis or mania and too little could worsen depression or anergia.
Peter J (frequent lurker, rare poster)
poster:PeterJ
thread:976934
URL: http://www.dr-bob.org/babble/20110115/msgs/977332.html