Posted by ace on December 5, 2010, at 23:59:24
In reply to Seroquel for unipolar depression, posted by sk85 on December 5, 2010, at 12:24:03
> Maybe this has been asked before.
> I'm suffering from unipolar depression and wondering if Seroquel as a monotheraphy would be of help. Can anyone share their experiences with Seroquel as a mood booster? What was the dose and did it matter a lot?From my own experience and from what i have seen, I really don't think seroquel would be a good choice for a pure depressive problem. certainly not a first line treatment. When used with other agents I believe it can have a synergistic effect, but I would recommend as first line a TCA or an MAOI. But these can have pronounce s/effects (as can Seroquel- esp weight gain)
> Also does it like SSRIs cause worsening of symptoms in the initial phase of treatment. I seem to be especially sensitive to that effect as
On the whole, and after a great deal of research and observation and experience, i have not really seen the SSRI's to be off great value in the treatment of any psychopathology. They can have horrid withdrawal syndromes, a myriad of s/effects (sometimes totally unexpected ones).
However, i am sure they do work for some. I just can't recommend them personally.
some pills have made me really depressed initially before giving an antidepressant effect.This, a lot of the time CAN, predict a very good therapeutic response. But even this phenomenon- the initial worsening of symptoms leading to a greater antidepressant effect- I have not seen it much, if at all, in the SSRI's either.
Unfortunately all the poor doctors are taught "SSRI's, SSRI's, SSRI's!!!!!" "They are the way!!" And they simply don't have the time to do their own independent research.
If SSRI's were taken off the market tomorrow, i don't think it would be such a bad thing.
Like I said, i would personally try a TCA or an MAOI.
All the best!
poster:ace
thread:972589
URL: http://www.dr-bob.org/babble/20101203/msgs/972654.html