Posted by SLS on October 25, 2010, at 5:08:06
In reply to I think dosing is an issue..., posted by Christ_empowered on October 24, 2010, at 14:40:01
> I mean, its one thing when they're very careful with the dosage of perphenazine (or other old-school AP); its quite another when you have some hospital shrink who just drugs people up with the cheapest available drug (yes, it happened to me).
>
> I think a lot of the "conventional" neuroleptics would probably have a much better reputation if docs had given them in small tranquilizing doses back in the day instead of dosing all the way up to EPS/Parkinson's as a matter or routine.
>
> That said: I've been on what I think was relatively low-dose Haldol, along with Ativan and Benadryl (hospital situation, not my idea). When I got switched over to Risperdal the next day, I immediately felt somewhat better...when I got switched over to Abilify, I felt even better.
>
>Just remember what was the target population when the antipsychotics first were discovered. They were used primarily for severe schizophrenia, many suffers of which were chronically institutionalized. I think the dosage guidelines were formulated empirically for these subjects rather than people with depression or anxiety.
It is not unusual for the clinical properties of a drug to become better elucidated as it is used over the years. I would be interested to see something describing the dosage differences used between the severest forms of schizophrenia versus affective or anxiety disorders for both old and new neuroleptics.
- ScottThe measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:966775
URL: http://www.dr-bob.org/babble/20101020/msgs/966905.html