Posted by KarenRB53 on October 7, 2010, at 9:06:30
In reply to Re: Advice please re. clomipramine/anafranil, posted by hopefullynow on May 27, 2010, at 13:58:34
> Hello,
> Anafranil is a very potent AD, even in small doses.I am currently on Anafranil 100mg/day and in the very beginning i started with 10 mg pills.
>
> I felt an robust improvement even at this small dose.What I felt when i increased to 100 mg/day, was that the major improvement were at relative small doses 50-75 mg, when i reached 150 mg/day the side effects couteracted the feelin good sensation and the diffenece in efficacity was minimal.
>
> Anafranil is a very potent AD which targets serotonin in the first place and norepinephrine in the second.Thru his 5-HT2a antagonism it should target dopamine, but i don't think it does too much as long as I encounter elevated prolactine levels.
>
> For me Anafranil is the foundation of the treatment but I had to introduce in my regimen an norephrinergic agent to reach remission.First was maprotiline, but being too sedating, now i'm experiencing with low dose Wellbutrin with nice results.
>
> Best regards!How much Wellbutrin are you using and is it immediate releae, SR or XL?
poster:KarenRB53
thread:949082
URL: http://www.dr-bob.org/babble/20100926/msgs/965001.html